Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53‐P21 axis, TGF‐beta signaling and focal adhesion that is TLR4 dependent
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.08.040
Abstract: ABSTRACT SsnB previously showed a promising role to lessen liver inflammation observed in a mouse model of NAFLD. Since NAFLD can progress to fibrosis, studies were designed to unravel its role in attenuating NAFLD associated… read more here.
Keywords: focal adhesion; fibrosis; ssnb; tlr4 ... See more keywords
Anti-Inflammatory Effect of Sparstolonin B through Inhibiting Expression of NF-κB and STAT-1
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810213
Abstract: Sparstolonin B (SsnB), which is found in Sparganium stoloniferum, prevents the synthesis of inflammatory mediators and is related to functional pathways of survival. In this study, we assessed the possible protective functions of SsnB on… read more here.
Keywords: expression; anti inflammatory; sparstolonin; expression stat ... See more keywords