Hippocampal interneurons are direct targets for circulating glucocorticoids
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25322
Abstract: The hippocampus has become a significant target of stress research in recent years because of its role in cognitive functioning, neuropathology, and regulation of the hypothalamic–pituitary–adrenal (HPA) axis. Despite the pervasive impact of stress on… read more here.
Keywords: stress; interneurons direct; sst interneurons; direct targets ... See more keywords
Arid1b haploinsufficiency in parvalbumin- or somatostatin-expressing interneurons leads to distinct ASD-like and ID-like behavior
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-64066-5
Abstract: Inhibitory interneurons are essential for proper brain development and function. Dysfunction of interneurons is implicated in several neurodevelopmental disorders, including autism spectrum disorder (ASD) and intellectual disability (ID). We have previously shown that Arid1b haploinsufficiency… read more here.
Keywords: asd like; parvalbumin somatostatin; arid1b haploinsufficiency; haploinsufficiency ... See more keywords
Early Excitatory Activity-Dependent Maturation of Somatostatin Interneurons in Cortical Layer 2/3 of Mice.
Sign Up to like & getrecommendations! Published in 2018 at "Cerebral cortex"
DOI: 10.1093/cercor/bhy293
Abstract: GABAergic interneurons perform distinct functions during cortical development in the mouse brain. Among the diverse GABAergic neurons present in the brain, early-born somatostatin (SST)-expressing inhibitory interneurons, which are innervated by other interneurons and local pyramidal… read more here.
Keywords: sst interneurons; maturation; early excitatory; activity ... See more keywords
Cortical interneurons: fit for function and fit to function? Evidence from development and evolution
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2023.1172464
Abstract: Cortical inhibitory interneurons form a broad spectrum of subtypes. This diversity suggests a division of labour, in which each cell type supports a distinct function. In the present era of optimisation-based algorithms, it is tempting… read more here.
Keywords: function; sst interneurons; development; fit function ... See more keywords
Cell-type-specific synaptic modulation of mAChR on SST and PV interneurons
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.1070478
Abstract: The muscarinic acetylcholine receptor (mAChR) antagonist, scopolamine, has been shown to have a rapid antidepressant effect. And it is believed that GABAergic interneurons play a crucial role in this action. Therefore, characterizing the modulation effects… read more here.
Keywords: machr; sst interneurons; modulation; type specific ... See more keywords