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Published in 2019 at "Journal of comparative pathology"
DOI: 10.1016/j.jcpa.2018.11.002
Abstract: The neuropeptide somatostatin (SST) plays an important regulatory role in the proliferation of normal and neoplastic cells. Five subtypes of somatostatin receptors (SSTRs), SSTR1-SSTR5, have been identified in human tumours. The SSTR2 subtype is identified…
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Keywords:
meningiomas;
meningioma;
expression;
canine meningioma ... See more keywords
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Published in 2019 at "Cancers"
DOI: 10.3390/cancers11060767
Abstract: Pulmonary carcinoids are a type of neuroendocrine tumor (NET) accounting for 1–2% of lung cancer cases. Currently, Positron Emission Tomography (PET)/CT based on the radiolabeled sugar analogue [18F]-FDG is used to diagnose and stage pulmonary…
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Keywords:
pulmonary carcinoid;
sstr2 expression;
carcinoid;
histone deacetylase ... See more keywords
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Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14010173
Abstract: Background: To improve peptide receptor radionuclide therapy (PRRT), we aimed to enhance the expression of somatostatin type-2 receptors (SSTR2) in vitro and in vivo, using valproic acid (VPA). Methods: Human NCI-H69 small-cell lung carcinoma cells…
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Keywords:
vitro vivo;
vpa;
177lu dotatate;
sstr2 expression ... See more keywords