Synapse topology and downmodulation events determine the functional outcome of anti-CD19 T cell-redirecting strategies
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DOI: 10.1080/2162402x.2022.2054106
Abstract: ABSTRACT Cancer immunotherapy strategies based on the endogenous secretion of T cell-redirecting bispecific antibodies by engineered T lymphocytes (STAb-T) are emerging as alternative or complementary approaches to those based on chimeric antigen receptors (CAR-T). The… read more here.
Keywords: stab cells; topology; cd19; anti cd19 ... See more keywords