Articles with "stabilin" as a keyword



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Macrophagic Stabilin-1 Restored Disruption of Vascular Integrity Caused by Sepsis.

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Published in 2018 at "Thrombosis and haemostasis"

DOI: 10.1055/s-0038-1669477

Abstract: Sepsis develops because of overwhelming inflammatory responses to bacterial infection, and disrupts vascular integrity. Stabilin-1 (STAB-1) is a phagocytic receptor, which mediates efferocytosis in a phosphatidylserine (PS)-dependent manner. STAB-1 is expected to play important roles… read more here.

Keywords: sepsis; stabilin; stab; vascular integrity ... See more keywords
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Tumor-associated macrophages respond to chemotherapy by detrimental transcriptional reprogramming and suppressing stabilin-1 mediated clearance of EGF

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1000497

Abstract: Introduction Tumor resistance to chemotherapy and metastatic relapse account for more than 90% of cancer specific mortality. Tumor-associated macrophages (TAMs) can process chemotherapeutic agents and impair their action. Little is known about the direct effects… read more here.

Keywords: clearance; egf; stabilin; associated macrophages ... See more keywords
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Ligand Binding and Signaling of HARE/Stabilin-2

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Published in 2019 at "Biomolecules"

DOI: 10.3390/biom9070273

Abstract: The Stabilin receptors are a two-member family in the type H class of scavenger receptors. These dynamic receptors bind and internalize multiple ligands from the cell surface for the purpose of clearing extracellular material including… read more here.

Keywords: stabilin; ligand binding; hare stabilin; signaling hare ... See more keywords
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BRAFV600E Expression in Thyrocytes Causes Recruitment of Immunosuppressive STABILIN-1 Macrophages

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14194687

Abstract: Papillary thyroid carcinoma (PTC) is the most frequent histological subtype of thyroid cancers (TC), and BRAFV600E genetic alteration is found in 60% of this endocrine cancer. This oncogene is associated with poor prognosis, resistance to… read more here.

Keywords: stabilin macrophages; stabilin; recruitment immunosuppressive; brafv600e expression ... See more keywords

Accumulation of stabilin-1 positive macrophages in the early stage of gastric cancer is associated with short cumulative survival

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Published in 2020 at "Oncology Letters"

DOI: 10.3892/ol.2020.11310

Abstract: The scavenger receptor stabilin-1 has been reported to be expressed by tumor-associated macrophages (TAMs) and to facilitate tumor growth and metastasis in mouse models of breast carcinoma and melanoma. However, to the best of our… read more here.

Keywords: stabilin; gastric cancer; tnm stage; stabilin positive ... See more keywords