Thermal stabilisation of the short DNA duplexes by acridine-4-carboxamide derivatives
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DOI: 10.1093/nar/gkac777
Abstract: Abstract The short oligodeoxynucleotide (ODN) probes are suitable for good discrimination of point mutations. However, the probes suffer from low melting temperatures. In this work, the strategy of using acridine-4-carboxamide intercalators to improve thermal stabilisation… read more here.
Keywords: short dna; point mutations; thermal stabilisation; stabilisation ... See more keywords