Mechanistic Evaluation of the Stability of Arylvinyl-1,2,4-trioxanes under Acidic Conditions for Their Oral Administration as an Antimalarial Drug
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DOI: 10.1021/acsomega.2c01321
Abstract: A mechanistic approach to understand the course of metabolism for synthetic 1,2,4-trioxanes, potent antimalarial compounds, to evaluate their bioavailability for antimalarial action has been studied in the present work. It is an important parameter to… read more here.
Keywords: stability arylvinyl; mechanistic evaluation; arylvinyl trioxanes; drug ... See more keywords