Investigating the Stability of DNA Duplex Hairpins using Optical Tweezers
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.412
Abstract: Covalent modifications and replication errors lead to DNA damage and mutation. Such errors occur frequently throughout the genome, disrupting the stability of the double helix. The 8-oxoguanine (8-oxoG) lesion, one of the most widespread forms… read more here.
Keywords: investigating stability; stability dna; duplex hairpins; stability ... See more keywords
Thermodynamic Stability of DNA Duplexes Comprising the Simplest T → dU Substitutions.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b00676
Abstract: Members of the uracil-DNA glycosylase (UDG) enzyme family recognize and bind uracil, sequestering it within the binding site pocket and catalyzing the cleavage of the base from the deoxyribose, leaving an abasic site. The recognition… read more here.
Keywords: nearest neighbor; dna; dna duplexes; stability dna ... See more keywords
CtBP1/2 differentially regulate genomic stability and DNA repair pathway in high-grade serous ovarian cancer cell
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DOI: 10.1038/s41389-021-00344-9
Abstract: The C-terminal binding proteins (CtBPs), CtBP1 and CtBP2, are transcriptional co-repressor that interacts with multiple transcriptional factors to modulate the stability of chromatin. CtBP proteins were identified with overexpression in the high-grade serous ovarian carcinoma… read more here.
Keywords: serous ovarian; dna; stability dna; genomic stability ... See more keywords
Structural Influence on the Post-Clustering Stability of DNA/AgNCs Fluorescence
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DOI: 10.3390/nano9050667
Abstract: DNA-encapsulated Silver Nanoclusters (DNA/AgNCs) based sensors have gained increasing attention in past years due to their diverse applications in bioimaging, biosensing, and enzymatic assays. Given the potential of DNA/AgNCs for practical applications, the systematic studies… read more here.
Keywords: stability dna; fluorescence; dna agncs; dna ... See more keywords