Improving Viscosity and Stability of a Highly Concentrated Monoclonal Antibody Solution with Concentrated Proline
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutical Research"
DOI: 10.1007/s11095-018-2398-1
Abstract: PurposeTo explain the effects of the osmolyte proline on the protein-protein interactions (PPI), viscosity and stability of highly concentrated antibody solutions in contrast to other neutral osmolytes.MethodsThe viscosity of ~225 mg/mL mAb solutions was measured with… read more here.
Keywords: viscosity; stability highly; highly concentrated; viscosity stability ... See more keywords
Stability of a highly dealuminated Y-zeolite in liquid aqueous media
Sign Up to like & getrecommendations! Published in 2019 at "Microporous and Mesoporous Materials"
DOI: 10.1016/j.micromeso.2019.02.014
Abstract: Abstract A dealuminated Y-zeolite with a nSi/nAl ratio of 130 is treated in pure water and aqueous solutions of NaCl at different pH values between 3 and 7 at 100 °C for up to 3 weeks. The… read more here.
Keywords: micropore volume; water; zeolite liquid; highly dealuminated ... See more keywords