Predicting the stability of human lysozyme mutants using the tree-based classifier TTOSOM
Sign Up to like & getrecommendations! Published in 2017 at "Chemometrics and Intelligent Laboratory Systems"
DOI: 10.1016/j.chemolab.2017.01.002
Abstract: Abstract One of the primary goals of applied proteomics is the development of new computational methods for modeling the properties of the proteins from the primary structure. In this work, we used the concept of… read more here.
Keywords: lysozyme mutants; human lysozyme; tree based; biology ... See more keywords
Simulation analysis of selective alanine mutation effect on stability of human prion protein
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2022.2036237
Abstract: Abstract Prion diseases are neurodegenerative disorders caused by spongiform degeneration of the brain. Understanding the fundamental mechanism of prion protein aggregation caused by mutations is very crucial to resolve the pathology of prion diseases. To… read more here.
Keywords: prion; prion protein; stability human; human prion ... See more keywords