Conversion and Stability of New Metabolites of Paralytic Shellfish Toxins under Different Temperature and pH Conditions.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b07063
Abstract: A number of new C-11 hydroxyl metabolites (so-called M-toxins) of paralytic shellfish toxins (PSTs) have been discovered in contaminated shellfish, and trace amounts have also been detected in some strains of PST-producing microalgae. To investigate… read more here.
Keywords: temperature; shellfish toxins; conversion stability; paralytic shellfish ... See more keywords
In Vitro Studies on Physiological and Chemical Stability of New LE404-Derivatives with Extended Half-Life.
Sign Up to like & getrecommendations! Published in 2018 at "Drug research"
DOI: 10.1055/s-0044-102096
Abstract: Dibenzoazecines are a class of potential neuroleptics with high affinity to dopamine and serotonin receptors. The efficacy and high therapeutic range has already been demonstrated in vivo with the lead structure 7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecin-3-ol (LE404: ) and… read more here.
Keywords: physiological chemical; chemical stability; studies physiological; stability ... See more keywords
Hydrolytic Stability of New Amino Acids Analogues of Memantine
Sign Up to like & getrecommendations! Published in 2020 at "Scientia Pharmaceutica"
DOI: 10.3390/scipharm88030038
Abstract: In the present work, the hydrolytic stability of new memantine analogues modified with amino acids, at different pH corresponding to the human biological liquids and organs, was evaluated. Memantine is an uncompetitive N-methyl-d-aspartate receptor antagonist… read more here.
Keywords: amino acids; mem; ala mem; hydrolytic stability ... See more keywords