The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2.
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DOI: 10.1073/pnas.2213715120
Abstract: The nuclear long non-coding RNA LUCAT1 has previously been identified as a negative feedback regulator of type I interferon and inflammatory cytokine expression in human myeloid cells. Here, we define the mechanistic basis for the… read more here.
Keywords: disease; stability nr4a2; inflammatory disease; expression ... See more keywords