Physicomechanical, stability, and pharmacokinetic evaluation of aceclofenac dimethyl urea cocrystals.
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DOI: 10.1208/s12249-021-01938-7
Abstract: Poor physicomechanical properties and limited aqueous solubility restrict the bioavailability of aceclofenac when given orally. To improve its above properties, aceclofenac (ACE) was cocrystallized with dimethyl urea (DMU) in 1:2 molar ratio by dry and… read more here.
Keywords: pharmacokinetic evaluation; stability pharmacokinetic; dimethyl urea; aceclofenac ... See more keywords