Articles with "stability vitro" as a keyword



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Lipid nanoparticles with fats or oils containing β-carotene: Storage stability and in vitro digestibility kinetics.

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Published in 2019 at "Food chemistry"

DOI: 10.1016/j.foodchem.2018.11.039

Abstract: The aim of this work was to study the formation of lipid nanoparticles (LNPs) with low (corn and olive oil) or high temperature melting lipids (cocoa butter and hydrogenated coconut oil). Moreover, their β-carotene stability… read more here.

Keywords: vitro digestibility; carotene; lipid nanoparticles; stability vitro ... See more keywords

Hispolon-Loaded Liquid Crystalline Nanoparticles: Development, Stability, In Vitro Delivery Profile, and Assessment of Hepatoprotective Activity in Hepatocellular Carcinoma

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Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.1c06796

Abstract: The present work describes the development and characterization of liquid crystalline nanoparticles of hispolon (HP-LCNPs) for treating hepatocellular carcinoma. HP-LCNPs were prepared by a top-down method utilizing GMO as the lipid and Pluronic F-127 as… read more here.

Keywords: hepatocellular carcinoma; stability vitro; crystalline nanoparticles; development ... See more keywords
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Effect of the type of N-substituent in the benzo-18-azacrown-6 compound on copper(II) chelation: complexation, radiolabeling, stability in vitro, and biodistribution in vivo.

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Published in 2023 at "Dalton transactions"

DOI: 10.1039/d3dt00742a

Abstract: In this work, we synthesized two new benzo-18-azacrown-6 ethers bearing picolinate and pyridine pendant arms and studied the copper complexes of these ligands, as well as those of an acetate analog. All considered ligands were… read more here.

Keywords: vitro biodistribution; stability vitro; copper; coordination ... See more keywords

Evaluation of Stability and In Vitro Security of Nanoemulsions Containing Eucalyptus globulus Oil

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Published in 2017 at "BioMed Research International"

DOI: 10.1155/2017/2723418

Abstract: Essential oil of Eucalyptus globulus presents several pharmacological properties. However, their therapeutic efficacy may be affected by limitations due to several conditions, rendering it difficult to obtain stable and effective pharmaceutical formulations. The use of… read more here.

Keywords: eucalyptus globulus; nanoemulsions containing; stability vitro; oil ... See more keywords
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Co-amorphous Drug Delivery Systems: a Review of Physical Stability, In Vitro and In Vivo Performance

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Published in 2022 at "AAPS PharmSciTech"

DOI: 10.1208/s12249-022-02421-7

Abstract: Over the past few decades, co-amorphous solids have been used as a promising approach for delivering poorly water-soluble drugs. Co-amorphous solids, comprising pharmacologically relevant drug substances or excipients, improve physical stability, solubility, dissolution, and bioavailability… read more here.

Keywords: stability vitro; vitro vivo; amorphous solids; physical stability ... See more keywords

Stability and In Vitro Aerodynamic Studies of Inhalation Powders Containing Ciprofloxacin Hydrochloride Applying Different DPI Capsule Types

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Published in 2021 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics13050689

Abstract: In the case of capsule-based dry powder inhalation systems (DPIs), the selection of the appropriate capsule is important. The use of gelatin, gelatin-PEG, and HPMC capsules has become widespread in marketed capsule-based DPIs. We aimed… read more here.

Keywords: capsule types; capsule; vitro aerodynamic; aerodynamic studies ... See more keywords
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Amorphous Solid Dispersions: Role of the Polymer and Its Importance in Physical Stability and In Vitro Performance

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14081747

Abstract: Amorphous solid dispersions stabilized by one or more polymer(s) have been widely used for delivering amorphous drugs with poor water solubilities, and they have gained great market success. Polymer selection is important for preparing robust… read more here.

Keywords: solid dispersions; stability vitro; amorphous solid; polymer ... See more keywords