Stabilized β-Hairpin Peptide Inhibits Insulin Degrading Enzyme.
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DOI: 10.1021/acs.jmedchem.8b00418
Abstract: Insulin-degrading enzyme (IDE) plays a critical role in both the proteolytic degradation and inactivation of insulin. The exploration of novel IDE inhibitors could aid in the study of novel therapeutics for type-2 diabetes. Herein, we… read more here.
Keywords: peptide; degrading enzyme; insulin degrading; hairpin peptide ... See more keywords