Application of Inflammatory Markers in Induced Sputum in Stable Chronic Obstructive Pulmonary Disease Patients with Positive Bronchodilation Tests
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DOI: 10.1007/s11596-019-2074-7
Abstract: SummaryPositive bronchodilation (BD) tests can be noticed in some stable chronic obstructive pulmonary disease (COPD) patients. The characteristics of airway inflammation in this entity remain unclear. Our study aimed to identify the characteristics of airway… read more here.
Keywords: positive tests; patients positive; copd patients; induced sputum ... See more keywords
Effects of Tiotropium Combined with Theophylline on Stable COPD Patients of Group B, D and its Impact on Small Airway Function: A Randomized Controlled Trial
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DOI: 10.1007/s12325-018-0831-9
Abstract: IntroductionTiotropium bromide has been widely used in clinical practice, while theophylline is another treatment option for chronic obstructive pulmonary disease (COPD). However, only a few relevant studies have investigated the long-term outcomes and efficacy of… read more here.
Keywords: airway function; treatment; group; small airway ... See more keywords
Frailty Assessment in a Stable COPD Cohort: Is There a COPD-Frail Phenotype?
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DOI: 10.1080/15412555.2021.1975670
Abstract: Abstract The frailty syndrome increases the morbidity/mortality in older adults, and several studies have shown a higher prevalence of this syndrome in patients with Chronic Obstructive Pulmonary Disease (COPD). The aim of this study was… read more here.
Keywords: phenotype; copd frail; copd; frailty ... See more keywords
The Microbiome in Bronchial Biopsies from Smokers and Ex-Smokers with Stable COPD - A Metatranscriptomic Approach
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DOI: 10.1080/15412555.2022.2033193
Abstract: Abstract Current knowledge about the respiratory microbiome is mainly based on 16S ribosomal RNA gene sequencing. Newer sequencing approaches, such as metatranscriptomics, offer the technical ability to measure the viable microbiome response to environmental conditions… read more here.
Keywords: host microbiome; smokers smokers; bronchial biopsies; stable copd ... See more keywords
Correlation of Inhaled Long-acting Bronchodilators with Adverse Cardiovascular Outcomes in Patients with Stable COPD: A Bayesian Network Meta-Analysis of Randomized Controlled Trials.
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DOI: 10.1097/fjc.0000000000000705
Abstract: A majority of existing studies have focused on the efficacy of inhaled long-acting bronchodilators (ILABs), such as long-acting muscarinic antagonists (LAMAs) and long-acting β2-agonists (LABAs), and LABAs combined with LAMAs in treating chronic obstructive pulmonary… read more here.
Keywords: meta analysis; stable copd; patients stable; long acting ... See more keywords
The acupuncture-related therapy for stable chronic obstructive pulmonary disease
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DOI: 10.1097/md.0000000000028832
Abstract: Supplemental Digital Content is available in the text Abstract Background: Chronic obstructive pulmonary disease (COPD) has become a huge economic burden. Increasing randomized clinical trials have favored the efficacy of a specified kind of acupuncture-related… read more here.
Keywords: copd; acupuncture related; obstructive pulmonary; stable copd ... See more keywords
Nasal high flow therapy and PtCO2 in stable COPD: A randomized controlled cross‐over trial
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DOI: 10.1111/resp.13185
Abstract: Hypercapnia is associated with worse clinical outcomes in exacerbations of COPD. The present study aimed to determine the effects of nasal high flow (NHF) therapy on transcutaneous partial pressure of carbon dioxide (PtCO2) in stable… read more here.
Keywords: ptco2 stable; stable copd; high flow; nasal high ... See more keywords
Bronchial inflammation and bacterial load in stable COPD is associated with TLR4 overexpression
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DOI: 10.1183/13993003.02006-2016
Abstract: Toll-like receptors (TLRs) and nucleotide-binding oligomerisation domain (NOD)-like receptors (NLRs) are two major forms of innate immune sensors but their role in the immunopathology of stable chronic obstructive pulmonary disease (COPD) is incompletely studied. Our… read more here.
Keywords: bacterial load; inflammation; copd; copd associated ... See more keywords
Aspiration and severe exacerbations in COPD: a prospective study
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DOI: 10.1183/23120541.00735-2020
Abstract: Rationale Swallow may be compromised in COPD leading to aspiration and adverse respiratory consequences. However, prevalence and consequences of detectable aspiration in stable COPD are not known. Objectives We tested the hypothesis that a significant… read more here.
Keywords: aecopd; exacerbations copd; stable copd; study ... See more keywords
Proteomic profiling of peripheral blood neutrophils identifies two inflammatory phenotypes in stable COPD patients
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DOI: 10.1186/s12931-017-0586-x
Abstract: BackgroundCOPD is a heterogeneous chronic inflammatory disease of the airways and it is well accepted that the GOLD classification does not fully represent the complex clinical manifestations of COPD and this classification therefore is not… read more here.
Keywords: blood neutrophils; copd patients; copd; peripheral blood ... See more keywords
Expiratory central airway collapse in stable COPD and during exacerbations
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DOI: 10.1186/s12931-017-0646-2
Abstract: BackgroundTracheal obstruction resulting from expiratory tracheal deformation has been associated with respiratory symptoms and severe airway exacerbations. In chronic obstructive pulmonary disease (COPD), acute exacerbations (AECOPD) create large intrathoracic pressure swings which may increase tracheal… read more here.
Keywords: aecopd; central airway; collapse; copd ... See more keywords