Construction of Highly Stable Cytotoxic Nuclear-Directed Ribonucleases
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DOI: 10.3390/molecules23123273
Abstract: Ribonucleases are proteins whose use is promising in anticancer therapy. We have previously constructed different human pancreatic ribonuclease variants that are selectively cytotoxic for tumor cells by introducing a nuclear localization signal into their sequence.… read more here.
Keywords: stable cytotoxic; nuclear directed; cytotoxic; construction highly ... See more keywords