Binding of LAG-3 to stable peptide-MHC class II limits TÂ cell function and suppresses autoimmunity and anti-cancer immunity.
Sign Up to like & getrecommendations! Published in 2022 at "Immunity"
DOI: 10.1016/j.immuni.2022.03.013
Abstract: Lymphocyte activation gene-3 (LAG-3) is a potent inhibitory co-receptor; yet, its functional ligand remains elusive, with distinct potential ligands identified. Here, we investigated the relative contribution of potential ligands, stable peptide-MHC class II complexes (pMHCII)… read more here.
Keywords: lag; stable pmhcii; cancer immunity; anti cancer ... See more keywords