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Published in 2019 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs18-4782
Abstract: We have engineered a tumor-targeted, microbial immunotherapy platform called STACT (S almonella T yphimurium (Attenuated) and Checkpoint Therapy). The platform strain has been engineered to increase tumor-specific enrichment, reduce immunosuppressive inflammation and enhance tolerability. Upon…
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Keywords:
platform strain;
tumor microenvironment;
platform;
tumor ... See more keywords