Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12)
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DOI: 10.1021/acsomega.2c01099
Abstract: The catechol derivative RC-12 (WR 27653) (1) is one of the few non-8-aminoquinolines with good activity against hypnozoites in the gold-standard Plasmodium cynomolgi–rhesus monkey (Macaca mulatta) model, but in a small clinical trial, it had… read more here.
Keywords: liver; profile; liver stage; activity ... See more keywords