4,9‐Diaminoacridines and 4‐Aminoacridines as Dual‐Stage Antiplasmodial Hits
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DOI: 10.1002/cmdc.202000740
Abstract: Multi‐stage drugs have been prioritized in antimalarial drug discovery, as targeting more than one process in the Plasmodium life cycle is likely to increase efficiency, while decreasing the chances of emergence of resistance by the… read more here.
Keywords: dual stage; aminoacridines dual; stage antiplasmodial; diaminoacridines aminoacridines ... See more keywords
4-Substituted Thieno[3,2-d]pyrimidines as Dual-Stage Antiplasmodial Derivatives
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DOI: 10.3390/ph15070820
Abstract: Malaria remains one of the major health problems worldwide. The increasing resistance of Plasmodium to approved antimalarial drugs requires the development of novel antiplasmodial agents that can effectively prevent and/or treat this disease. Based on… read more here.
Keywords: substituted thieno; pyrimidines dual; thieno pyrimidines; stage ... See more keywords