Brentuximab vedotin plus doxorubicin, vinblastine, and dacarbazine in patients with advanced‐stage, classical Hodgkin lymphoma: A prespecified subgroup analysis of high‐risk patients from the ECHELON‐1 study
Sign Up to like & getrecommendations! Published in 2021 at "Hematological Oncology"
DOI: 10.1002/hon.2838
Abstract: Approximately one‐third of patients diagnosed with Hodgkin lymphoma presenting with Stage IV disease do not survive past 5 years. We present updated efficacy and safety analyses in high‐risk patient subgroups, defined by Stage IV disease… read more here.
Keywords: risk; hodgkin lymphoma; high risk; stage disease ... See more keywords
Gallbladder Cancer: Complete Resection after Second Line Treatment in Stage IV Disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Gastrointestinal Cancer"
DOI: 10.1007/s12029-017-0044-5
Abstract: Gallbladder carcinoma is rare, with an incidence of 1.6–2.0/ 100,000 in Western Europe; however, it is the most common cancer of the biliary tract accounting for 80–95% of these cancers [1–3]. It is far more… read more here.
Keywords: gallbladder; treatment; stage disease; cancer ... See more keywords
CD10 inhibits cell motility but expression is associated with advanced stage disease in colorectal cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2018.04.002
Abstract: INTRODUCTION CD10 is a cell membrane-bound endopeptidase which is expressed in normal small bowel but not in normal colon. It is aberrantly expressed in a small proportion of colorectal cancers (CRC) and this has been… read more here.
Keywords: cell; expression; stage disease; cd10 ... See more keywords
Management and prognostic factors of epithelioid trophoblastic tumors: Results from the International Society for the Study of Trophoblastic Diseases database.
Sign Up to like & getrecommendations! Published in 2019 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2018.11.015
Abstract: OBJECTIVE Epithelioid Trophoblastic Tumor (ETT) is an extremely rare form of Gestational Trophoblastic Neoplasia (GTN). Knowledge on prognostic factors and optimal management is limited. We identified prognostic factors, optimal treatment, and outcome from the world's… read more here.
Keywords: surgery; prognostic factors; management; stage disease ... See more keywords
Encorafenib — a new agent for advanced-stage disease
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Clinical Oncology"
DOI: 10.1038/s41571-018-0019-x
Abstract: Anti-angiogenic therapy, predominantly with the anti-VEGF antibody bevacizumab, has not been shown to improve the survival of patients with breast cancer. 70% of patients with this disease are overweight or obese; now, data from 99… read more here.
Keywords: agent advanced; new agent; encorafenib new; stage disease ... See more keywords
High Prevalence of Late-Stage Disease in Newly Diagnosed Human Immunodeficiency Virus Patients in Sierra Leone
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy208
Abstract: Abstract A high prevalence of late-stage disease (75.4%) and severe immunosuppression (23.3%) was observed in 155 newly diagnosed human immunodeficiency virus patients in Freetown, Sierra Leone during August to November 2017. Within the late-stage diagnosis… read more here.
Keywords: late stage; prevalence late; high prevalence; stage disease ... See more keywords
Initial Stage of Disease Similar for White and Black Patients With Early-Onset Colorectal Cancer at a Safety-Net Hospital.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of clinical gastroenterology"
DOI: 10.1097/mcg.0000000000001840
Abstract: BACKGROUND Non-Hispanic Black (NHB) patients with early-onset colorectal cancer (EOCRC) are more likely to present with advanced-stage disease than their Non-Hispanic White (NHW) counterparts. To further elucidate whether differences in tumor biology or disparities in… read more here.
Keywords: safety net; disease; stage disease; nhb patients ... See more keywords
Clinical characteristics of Australian treatment‐naïve patients with classical Hodgkin lymphoma from the lymphoma and related diseases registry
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Haematology"
DOI: 10.1111/ejh.13915
Abstract: Comprehensive clinical characteristics of Australian patients with classical Hodgkin Lymphoma (cHL) have not previously been systematically collected and described. We report real‐world data of 498 eligible patients from the first 5 years of the Lymphoma and… read more here.
Keywords: treatment; stage disease; clinical characteristics; lymphoma ... See more keywords
Double‐negative T cells: Setting the stage for disease control or progression
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DOI: 10.1111/imm.13441
Abstract: Double‐negative (DN) T cells are present at relatively low frequencies in human peripheral blood, and are characterized as expressing the alpha‐beta or gamma‐delta T‐cell receptor (TCR), but not the CD4 nor the CD8 co‐receptors. Despite… read more here.
Keywords: negative cells; double negative; setting stage; cells setting ... See more keywords
High PD-L1 expression is associated with stage IV disease and poorer overall survival in 186 cases of small cell lung cancers
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14935
Abstract: Background Small cell lung cancer (SCLC) is an aggressive malignancy with a distinct natural history and dismal prognosis. SCLC is characterized as a recalcitrant neoplasm with limited therapeutic options and platinum-based chemotherapy is the treatment… read more here.
Keywords: high expression; sclc; expression; stage disease ... See more keywords
Carcinosarcomas of the Uterus: Prognostic Factors and Impact of Adjuvant Treatment
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Management and Research"
DOI: 10.2147/cmar.s309551
Abstract: Background Uncertainties remain about the most effective treatment for uterine carcinosarcoma (UCS), a rare but aggressive uterine cancer, due to the limited scope for randomized trials. This study investigates whether nodal excision or adjuvant therapies… read more here.
Keywords: carcinosarcomas uterus; treatment; disease; uterus prognostic ... See more keywords