Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads.
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DOI: 10.1021/acschembio.6b00939
Abstract: The broad-spectrum phosphonate antibiotic fosfomycin is currently in use for clinical treatment of infections caused by both Gram-positive and Gram-negative uropathogens. The antibiotic is biosynthesized by various streptomycetes, as well as by pseudomonads. Notably, the… read more here.
Keywords: enzymes involved; late stage; characterization two; stage enzymes ... See more keywords