Durvalumab After Chemoradiotherapy in Patients With Unresectable Stage III Non–Small Cell Lung Cancer
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DOI: 10.1001/jamanetworkopen.2024.7542
Abstract: This cohort study evaluates the characteristics, treatment patterns, and outcomes of patients with unresectable stage III non–small cell lung cancer who did or did not receive durvalumab. read more here.
Keywords: stage iii; patients unresectable; non small; small cell ... See more keywords
Role of Deficient DNA Mismatch Repair Status in Patients With Stage III Colon Cancer Treated With FOLFOX Adjuvant Chemotherapy: A Pooled Analysis From 2 Randomized Clinical Trials
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DOI: 10.1001/jamaoncol.2017.2899
Abstract: Importance The prognostic impact of DNA mismatch repair (MMR) status in stage III colon cancer patients receiving FOLFOX (folinic acid, fluorouracil, and oxaliplatin) adjuvant chemotherapy remains controversial. Objective To determine the association of MMR status… read more here.
Keywords: status; stage iii; iii colon; colon cancer ... See more keywords
Association Between Immune-Related Adverse Events and Recurrence-Free Survival Among Patients With Stage III Melanoma Randomized to Receive Pembrolizumab or Placebo: A Secondary Analysis of a Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2019.5570
Abstract: Importance Whether immune-related adverse events (irAEs) indicate drug activity in patients treated with immune checkpoint inhibitors remains unknown. Objective To investigate the association between irAEs and recurrence-free survival (RFS) in the double-blind EORTC 1325/KEYNOTE-054 clinical… read more here.
Keywords: melanoma; arm; stage iii; recurrence ... See more keywords
Comparing Trial and Real-world Adjuvant Oxaliplatin Delivery in Patients With Stage III Colon Cancer Using a Longitudinal Cumulative Dose.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.4445
Abstract: Importance Delivery of adjuvant chemotherapy can differ substantially between trial and real-world populations. Adherence metrics like relative dose intensity (RDI) cannot capture the timing of modifications and mask differences in the total amount of chemotherapy… read more here.
Keywords: oncology; trial; stage iii; colon cancer ... See more keywords
Mortality Risks Over 20 Years in Men With Stage I to III Hormone Receptor-Positive Breast Cancer.
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DOI: 10.1001/jamaoncol.2023.7194
Abstract: Importance In women with hormone receptor-positive (HR+) breast cancer, the risk of distant recurrence and death persists for at least 20 years from diagnosis. The risk of late mortality in men with HR+ breast cancer… read more here.
Keywords: bcsm; stage iii; breast cancer; breast ... See more keywords
Predictive Role of Circulating Tumor DNA in Stage III Colon Cancer Treated With Celecoxib: A Post Hoc Analysis of the CALGB (Alliance)/SWOG 80702 Phase 3 Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2025 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2025.5144
Abstract: Importance Observational studies have associated use of aspirin and selective cyclooxygenase inhibitors with decreased recurrence and improved survival in patients with colon cancer. While randomized clinical trials have not shown benefit across all patients, these… read more here.
Keywords: stage iii; cancer; analysis; ctdna ... See more keywords
Adjuvant Radiotherapy for Surgically Resected Stage III Merkel Cell Carcinoma.
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DOI: 10.1001/jamasurg.2023.7016
Abstract: This case-control study evaluates whether adjuvant radiotherapy is associated with overall survival among patients with surgically resected stage III Merkel cell carcinoma. read more here.
Keywords: stage iii; adjuvant radiotherapy; surgically resected; merkel cell ... See more keywords
Nomogram for predicting overall survival in stage II‐III colorectal cancer
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DOI: 10.1002/cam4.2896
Abstract: The overall survival (OS) of patients diagnosed with stage II‐III colorectal cancer (CRC) can vary greatly, even between patients with the same tumor stage. We aimed to design a nomogram to predict OS in resected,… read more here.
Keywords: stage iii; colorectal cancer; iii colorectal; overall survival ... See more keywords
A novel deep learning prognostic system improves survival predictions for stage III non‐small cell lung cancer
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DOI: 10.1002/cam4.4782
Abstract: Accurate prognostic prediction plays a crucial role in the clinical setting. However, the TNM staging system fails to provide satisfactory individual survival prediction for stage III non‐small cell lung cancer (NSCLC). The performance of the… read more here.
Keywords: non small; iii non; stage iii; small cell ... See more keywords
Real‐world KINDLE‐Latin America subset data on treatment patterns and clinical outcomes in patients with stage III non‐small‐cell lung cancer
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DOI: 10.1002/cam4.4990
Abstract: Stage III non‐small‐cell lung cancer (NSCLC) management is challenging given the heterogeneous nature of the disease. The LATAM subset of the real‐world, global KINDLE study reported the treatment patterns and clinical outcomes for LATAM from… read more here.
Keywords: non small; iii non; stage iii; small cell ... See more keywords
The new ‘coN’ staging system combining lymph node metastasis and tumour deposit provides a more accurate prognosis for TNM stage III colon cancer
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DOI: 10.1002/cam4.5099
Abstract: Despite controversy over its origin and definition, the significance of tumour deposit (TD) has been underestimated in the tumour node metastasis (TNM) staging system for colon cancer, especially in stage III patients. We aimed to… read more here.
Keywords: staging system; node metastasis; stage iii; colon cancer ... See more keywords