Late-stage C(sp2)–H and C(sp3)–H glycosylation of C-aryl/alkyl glycopeptides: mechanistic insights and fluorescence labeling†‡
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DOI: 10.1039/d0sc01260b
Abstract: C(sp3)–H and C(sp2)–H glycosylations of structurally complex amino acids and peptides were accomplished through the assistance of triazole peptide-isosteres. The palladium-catalyzed peptide–saccharide conjugation provided modular access to structurally complex C-alkyl glycoamino acids, glycopeptides and C-aryl… read more here.
Keywords: alkyl; late stage; sp2 sp3; stage sp2 ... See more keywords