Late-Stage C(sp3)-H Methylation of Drug Molecules.
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DOI: 10.1021/jacs.2c13396
Abstract: Methyl groups are well understood to play a critical role in pharmaceutical molecules, especially those bearing saturated heterocyclic cores. Accordingly, methods that install methyl groups onto complex molecules are highly coveted. Late-stage C-H functionalization is… read more here.
Keywords: methyl groups; drug molecules; stage sp3; late stage ... See more keywords