Melanocortin receptor agonist NDP-α-MSH improves cognitive deficits and microgliosis but not amyloidosis in advanced stages of AD progression in 5XFAD and 3xTg mice
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DOI: 10.3389/fimmu.2022.1082036
Abstract: Introduction Alzheimer’s disease (AD) is the most frequent cause of dementia and still lacks effective therapy. Clinical signs of AD include low levels of endogenous melanocortins (MCs) and previous studies have shown that treatment with… read more here.
Keywords: 3xtg mice; ndp msh; mice; stages progression ... See more keywords