Structure-Function Analysis of the A1 Subunit of Shiga Toxin 2 with Peptides That Target the P-Stalk Binding Site and Inhibit Activity.
Sign Up to like & getrecommendations! Published in 2024 at "Biochemistry"
DOI: 10.1021/acs.biochem.3c00733
Abstract: Shiga toxin 2a (Stx2a) is the virulence factor of Escherichia coli (STEC), which is associated with hemolytic uremic syndrome, the leading cause of pediatric kidney failure. The A1 subunit of Stx2a (Stx2A1) binds to the… read more here.
Keywords: ctd; subunit; stalk binding; stx2a1 ... See more keywords
Native Human Monoclonal Antibodies with Potent Cross-Lineage Neutralization of Influenza B Viruses
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DOI: 10.1128/aac.02269-17
Abstract: ABSTRACT Although antibodies that effectively neutralize a broad set of influenza viruses exist in the human antibody repertoire, they are rare. We used a single-cell screening technology to identify rare monoclonal antibodies (MAbs) that recognized… read more here.
Keywords: stalk binding; influenza viruses; monoclonal antibodies; human monoclonal ... See more keywords