Discrimination between Different DNA Lesions by Monitoring Single-Molecule Polymerase Stalling Kinetics during Nanopore Sequencing.
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DOI: 10.1021/acs.nanolett.2c01833
Abstract: O6-Carboxymethylguanosine (O6-CMG), O6-methylguanosine (O6-MeG), and abasic site (AP site) are DNA lesions induced by alkylating agents. Identification of these lesions in DNA may aid in understanding their relevance to carcinogenesis and may be used for… read more here.
Keywords: stalling kinetics; dna; dna lesions; different dna ... See more keywords