Rosiglitazone Phosphorylates Akt, Reduces Caspase 3 Activity and Enhances Mitochondrial Function in frozen Thawed Stallion Spermatozoa
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Equine Veterinary Science"
DOI: 10.1016/j.jevs.2018.05.047
Abstract: Spermatozoa surviving freezing thawing, experience changes that represent an acceleration of the default apoptotic dead pathway that the spermatozoa experience after ejaculation[1]. One key protein related to survival is the Akt, provided that this kinase… read more here.
Keywords: spermatozoa; mitochondrial function; thawed stallion; rosiglitazone ... See more keywords
Electrophilic aldehyde products of lipid peroxidation selectively adduct to heat shock protein 90 and arylsulfatase A in stallion spermatozoa
Sign Up to like & getrecommendations! Published in 2017 at "Biology of Reproduction"
DOI: 10.1095/biolreprod.116.145292
Abstract: Abstract Oxidative stress is a major determinant of mammalian sperm function stimulating lipid peroxidation cascades that culminate in the generation of potentially cytotoxic aldehydes. The aim of this study was to assess the impact of… read more here.
Keywords: heat shock; electrophilic aldehyde; stallion spermatozoa; lipid peroxidation ... See more keywords
Causative mechanisms and functional correlates of MTT reduction in stallion spermatozoa.
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DOI: 10.1530/rep-21-0464
Abstract: MTT is a commonly used cell vitality probe, due to its ability to form insoluble formazan deposits at cellular locations of intense oxidoreductase activity. Although this response is considered a reflection of mitochondrial redox activity,… read more here.
Keywords: reduction; stallion spermatozoa; mtt reduction; extra mitochondrial ... See more keywords