The deubiquitinase STAMBP modulates cytokine secretion through the NLRP3 inflammasome.
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DOI: 10.1016/j.cellsig.2020.109859
Abstract: The NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome is a multimeric, cytoplasmic, protein complex that regulates maturation and secretion of interleukin (IL)-1β, a potent pro-inflammatory cytokine. Critical to host defense against pathogens, IL-1β… read more here.
Keywords: deubiquitinase; secretion; deubiquitinase stambp; stambp modulates ... See more keywords