Optimal Evolution of the Standard Genetic Code.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular evolution"
DOI: 10.1007/s00239-020-09984-8
Abstract: The Standard Genetic Code (SGC) exists in every known organism on Earth. SGC evolution via early unique codon assignment, then later wobble, yields coding resembling the near-universal code. Below, later wobble is shown to also… read more here.
Keywords: evolution; code; codon assignment; optimal evolution ... See more keywords
On the Origin of Frameshift-Robustness of the Standard Genetic Code
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DOI: 10.1093/molbev/msab164
Abstract: Abstract The standard genetic code (SGC) has been extensively analyzed for the biological ramifications of its nonrandom structure. For instance, mismatch errors due to point mutation or mistranslation have an overall smaller effect on the… read more here.
Keywords: standard genetic; robustness; frameshift robustness; mismatch robustness ... See more keywords
Combinatorial Fusion Rules to Describe Codon Assignment in the Standard Genetic Code
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DOI: 10.3390/life11010004
Abstract: We propose combinatorial fusion rules that describe the codon assignment in the standard genetic code simply and uniformly for all canonical amino acids. These rules become obvious if the origin of the standard genetic code… read more here.
Keywords: fusion; genetic code; fusion rules; standard genetic ... See more keywords
Computational Analysis of Genetic Code Variations Optimized for the Robustness against Point Mutations with Wobble-like Effects
Sign Up to like & getrecommendations! Published in 2021 at "Life"
DOI: 10.3390/life11121338
Abstract: It is believed that the codon–amino acid assignments of the standard genetic code (SGC) help to minimize the negative effects caused by point mutations. All possible point mutations of the genetic code can be represented… read more here.
Keywords: point mutations; genetic code; code; robustness point ... See more keywords