OUTCOME OF AUTOLOGOUS STEM CELL TRANSPLANTATION IN MULTIPLE MYELOMA; EXPERIENCE FROM A SINGLE CENTER IN SAUDI ARABIA
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DOI: 10.1002/hon.240_2631
Abstract: del17p – 5.6% (9/159); 1p32/1q21 amp/del – 12% (19/159); hypodiploidy – 3.1% (5/159); hyperdiploidy – 1.25% (2/159); del5q – 0,6% (1/159); other – not found. Combination two aberrations was discovered in 11.9% (19/159) patients, complex… read more here.
Keywords: risk; risk msmart; median pfs; complex abnormalities ... See more keywords
Long-term outcomes of modified BFM-95 regimen in adults with newly diagnosed standard-risk acute lymphoblastic leukemia: a retrospective single-center study
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Hematology"
DOI: 10.1007/s12185-019-02703-0
Abstract: The standard treatment for adult acute lymphoblastic leukemia (ALL) is undefined. Patients with newly diagnosed standard-risk ALL at a single institution were retrospectively analyzed. From 2010 to 2017, 46 patients were treated using the modified… read more here.
Keywords: risk; newly diagnosed; lymphoblastic leukemia; standard risk ... See more keywords
Outcomes of Autologous Stem Cell Transplant (ASCT) in Patients with t (11;14) Multiple Myeloma(MM)
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DOI: 10.1016/j.bbmt.2019.12.486
Abstract: Introduction MM is a clonal disorder of malignant plasma cells. Standard of care for newly diagnosed MM is induction with triplet regimen chemotherapy followed by ASCT. Patients are stratified based on cytogenetic analysis as being… read more here.
Keywords: risk; newly diagnosed; high risk; standard risk ... See more keywords
Haploidentical transplantation compared with matched sibling and unrelated donor transplantation for adults with standard‐risk acute lymphoblastic leukaemia in first complete remission
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DOI: 10.1111/bjh.14854
Abstract: We retrospectively investigated outcomes of haploidentical donor (HID) transplant for adults with standard‐risk acute lymphoblastic leukaemia (ALL) in first complete remission (CR1) compared with human leucocyte antigen (HLA)‐matched sibling donor (MSD) and HLA‐matched unrelated donor… read more here.
Keywords: risk acute; year; standard risk; transplantation ... See more keywords
Impact of Autologous Transplantation in Patients with Multiple Myeloma with t(11;14): A Propensity-Score Matched Analysis
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DOI: 10.1158/1078-0432.ccr-19-0706
Abstract: Purpose: Patients with multiple myeloma with t(11;14) have been considered to have standard-risk disease. However, several recent reports have shown contradictory results. We identified 95 patients with multiple myeloma with t(11;14) on FISH studies, who… read more here.
Keywords: risk control; patients multiple; multiple myeloma; standard risk ... See more keywords
Improved Treatment of Childhood ALL in Malaysia
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DOI: 10.1182/blood-2019-129402
Abstract: The survival rate of childhood acute lymphoblastic leukemia (ALL) has reached >80-90% in developed countries, which is a triumph of modern medicine. This success is due to implementation of contemporary treatment protocols, optimal application of… read more here.
Keywords: risk group; risk; high risk; treatment ... See more keywords
Prevalence of Genetic Abnormalities in Patients with Multiple Myeloma and Its Clinical Relevance in a Developing Country like India
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DOI: 10.1182/blood-2020-141895
Abstract: Introduction Multiple myeloma (MM) is a malignancy involving terminally differentiated plasma cells. Its incidence in India is about 0.7/1,00,000 population amounting to about 6,800 new cases a year A number of genomic aberrations are associated… read more here.
Keywords: risk group; risk; fish analysis; high risk ... See more keywords
CD20 expression sub-stratifies standard-risk patients with B cell precursor acute lymphoblastic leukemia
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DOI: 10.18632/oncotarget.22207
Abstract: Patients with standard-risk adult acute lymphoblastic leukemia (ALL) treated with chemotherapy do not have satisfactory outcomes. To more precisely classify ALL patients and optimize treatment, we re-evaluated the risk stratification system by examining CD20 expression… read more here.
Keywords: risk; cd20 positive; standard risk; cd20 negative ... See more keywords
Carfilzomib, cyclophosphamide and dexamethasone for newly diagnosed, high-risk myeloma patients not eligible for transplant: a pooled analysis of two studies
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DOI: 10.3324/haematol.2019.243428
Abstract: Despite remarkable advances in the treatment of multiple myeloma (MM) in the last decades, the prognosis of patients harboring highrisk cytogenetic abnormalities remains dismal as compared to that of standard-risk patients. Proteasome inhibitors have been… read more here.
Keywords: risk; carfilzomib cyclophosphamide; high risk; analysis ... See more keywords