Universal protocol and standard-spiking strategy for profiling of host cell proteins in therapeutic growth hormone.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical biochemistry"
DOI: 10.2139/ssrn.4229856
Abstract: Liquid chromatography coupled to mass spectrometry (LC-MS) is widely used for host cell proteins (HCP) identification in antibody drug development because of its sensitivity, selectivity, and adaptability. However, LC-MS based identification of HCP in biotherapeutics… read more here.
Keywords: standard spiking; hcp; growth hormone; cell proteins ... See more keywords