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   Articles with "standard therapy" as a keyword



Synergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of glioma

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recommendations! Published in 2022 at "Translational Oncology"

DOI: 10.1016/j.tranon.2022.101368

Abstract: Highlights • A novel pair of orthotopic PDX models of glioma bearing IDH1-R132H/R132C mutations.• New mutant IDH1i (SY-435) with standard therapy led to strong therapeutic efficacy.• H3K4/K9 methylation/mtDNA-encoded molecules mediate anti-tumor activity of SYC-435.• Discovered… read more here.

Keywords: 435 standard; syc 435; models glioma; standard therapy ... See more keywords

Inhibition of Toxoplasma gondii by 1,2,4-triazole-based compounds: marked improvement in selectivity relative to the standard therapy pyrimethamine and sulfadiazine

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recommendations! Published in 2022 at "Journal of Enzyme Inhibition and Medicinal Chemistry"

DOI: 10.1080/14756366.2022.2112576

Abstract: Abstract A safer treatment for toxoplasmosis would be achieved by improving the selectivity profile of novel chemotherapeutics compared to the standard therapy pyrimethamine (PYR) and sulfadiazine (SDZ). We previously reported on the identification of the… read more here.

Keywords: therapy pyrimethamine; toxoplasma; standard therapy; toxoplasma gondii ... See more keywords

Meta-analysis of the prognostic efficacy of daratumumab combined with standard therapy in high-risk multiple myeloma.

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recommendations! Published in 2025 at "Hematology"

DOI: 10.1080/16078454.2025.2532893

Abstract: ABSTRACT Objective: This meta-analysis aims to evaluate the efficacy of daratumumab (DAR) in combination with standard therapy for the treatment of high-risk multiple myeloma (HRMM), offering evidence-based insights to guide clinical decision-making. Methods: A comprehensive… read more here.

Keywords: standard therapy; meta analysis; therapy; high risk ... See more keywords

CTNI-15. CLINICAL EFFECT OF KETOGENIC DIET COMBINED WITH STANDARD THERAPY INCLUDING BEVACIZUMAB FOR MALIGNANT GLIOMA

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recommendations! Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf201.0512

Abstract: Glioma exhibit an upregulated glucose-dependent metabolic pathway. Based on our previous study, we conducted a clinical study to evaluate the feasibility of combining standard therapy with a ketogenic diet in patients with malignant glioma. The… read more here.

Keywords: malignant glioma; ketogenic diet; standard therapy; case ... See more keywords
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665: IMPACT OF PHARMACIST INTERVENTION WITH PROCALCITONIN-GUIDED THERAPY IN ICU PATIENTS WITH PNEUMONIA

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recommendations! Published in 2018 at "Critical Care Medicine"

DOI: 10.1097/01.ccm.0000528680.68587.92

Abstract: Critical Care Medicine • Volume 46 • Number 1 (Supplement) www.ccmjournal.org Learning Objectives: Procalcitonin (PCT) is a peptide that is released in response to bacterial infections. The 2016 IDSA pneumonia guidelines recommend PCT to help… read more here.

Keywords: intervention; medicine; group; standard therapy ... See more keywords

Control of blood glucose levels by an artificial pancreas in patients with severe coronavirus disease 2019 pneumonia

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recommendations! Published in 2022 at "Artificial Organs"

DOI: 10.1111/aor.14472

Abstract: Abstract Background Many patients with severe coronavirus disease 2019 (COVID‐19) pneumonia experience hyperglycemia. It is often difficult to control blood glucose (BG) levels in such patients using standard intravenous insulin infusion therapy. Therefore, we used… read more here.

Keywords: coronavirus disease; severe coronavirus; patients severe; therapy ... See more keywords
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Osimertinib Is More Effective than Standard Therapy in EGFRT790M Tumors.

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recommendations! Published in 2017 at "Cancer discovery"

DOI: 10.1158/2159-8290.cd-rw2017-040

Abstract: Osimertinib achieved better responses than platinum-pemetrexed in patients with EGFRT790M lung cancer. read more here.

Keywords: effective standard; standard therapy; egfrt790m tumors; therapy egfrt790m ... See more keywords

Thrombotic Events in COVID-19 Patients Undergoing Convalescent Plasma Therapy: A Systematic Review

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recommendations! Published in 2021 at "Blood"

DOI: 10.1182/blood-2021-153374

Abstract: INTRODUCTION Convalescent plasma therapy (CPT) has been proposed as a mechanism of passive immunization against COVID-19. Current guidelines on the efficacy of its use is not well delineated with limited studies analyzing the risk of… read more here.

Keywords: review; risk; thrombotic events; therapy ... See more keywords

Total neoadjuvant therapy versus standard therapy in locally advanced rectal cancer: A systematic review and meta-analysis of 15 trials

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recommendations! Published in 2022 at "PLOS ONE"

DOI: 10.1371/journal.pone.0276599

Abstract: Background Neoadjuvant chemoradiotherapy (nCRT) before total mesorectal excision (TME) and followed systemic chemotherapy is widely accepted as the standard therapy for locally advanced rectal cancer (LARC). This meta-analysis was to evaluate the current evidence regarding… read more here.

Keywords: standard therapy; rectal cancer; meta analysis; therapy ... See more keywords

Edoxaban (LIXIANA®) in the treatment of venous thromboembolism.

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recommendations! Published in 2020 at "Future cardiology"

DOI: 10.2217/fca-2020-0139

Abstract: Standard therapy for venous thromboembolism (VTE) includes the use of heparins and vitamin K antagonists. Randomized clinical trials have shown that non-vitamin K oral anticoagulants are as effective and safe as standard therapy in VTE treatment,… read more here.

Keywords: venous thromboembolism; treatment; edoxaban lixiana; standard therapy ... See more keywords

Influence of adding strain-counterstrain to standard therapy on axioscapular muscles amplitude and fatigue in mechanical neck pain: a single-blind, randomized trial

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recommendations! Published in 2022 at "European Journal of Physical and Rehabilitation Medicine"

DOI: 10.23736/s1973-9087.22.07194-5

Abstract: BACKGROUND Strain-counterstrain technique (SCS) or positional release therapy is strongly recommended for patients with mechanical neck pain (MNP) because this method has excellent benefits, but the clinical significance of this method is unclear AIM The… read more here.

Keywords: neck pain; mechanical neck; therapy; pain ... See more keywords