Articles with "stapep" as a keyword



StaPep: An Open-Source Toolkit for Structure Prediction, Feature Extraction, and Rational Design of Hydrocarbon-Stapled Peptides

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Published in 2024 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.4c01718

Abstract: All-hydrocarbon stapled peptides, with their covalent side-chain constraints, provide enhanced proteolytic stability and membrane permeability, making them superior to linear peptides. However, tools for extracting structural and physicochemical descriptors to predict the properties of hydrocarbon-stapled… read more here.

Keywords: hydrocarbon stapled; toolkit; stapep; stapled peptides ... See more keywords