Articles with "staphylokinase" as a keyword



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Designing a multifunctional staphylokinase variant (SAK-2RGD-TTI) with appropriate thrombolytic activity in vitro

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Published in 2019 at "Biotechnology Letters"

DOI: 10.1007/s10529-019-02748-5

Abstract: Objective Thrombin, platelets, and plasmin are three key factors involved in hemostasis and thrombolysis. Thrombolytic therapy with clinically approved drugs is often followed by recurrent thrombosis caused by thrombin-induced platelet aggregation from the clot debris.… read more here.

Keywords: clot; 2rgd tti; staphylokinase; designing multifunctional ... See more keywords
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Hidden Potential of Highly Efficient and Widely Accessible Thrombolytic Staphylokinase.

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Published in 2022 at "Stroke"

DOI: 10.1161/strokeaha.122.040219

Abstract: Stroke burden is substantially increasing but current therapeutic drugs are still far from ideal. Here we highlight the vast potential of staphylokinase as an efficient, fibrin-selective, inexpensive, and evolvable thrombolytic agent. The emphasis is escalated… read more here.

Keywords: widely accessible; accessible thrombolytic; highly efficient; staphylokinase ... See more keywords