“Stapling” scFv for multispecific biotherapeutics of superior properties
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DOI: 10.1080/19420862.2023.2195517
Abstract: ABSTRACT Single-chain fragment variable (scFv) domains play an important role in antibody-based therapeutic modalities, such as bispecifics, multispecifics and chimeric antigen receptor T cells or natural killer cells. However, scFv domains exhibit lower stability and… read more here.
Keywords: biotherapeutics superior; stapling scfv; superior properties; multispecific biotherapeutics ... See more keywords