refTSS: A Reference Data Set for Human and Mouse Transcription Start Sites.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2019.04.045
Abstract: Transcription starts at genomic positions called transcription start sites (TSSs), producing RNAs, and is mainly regulated by genomic elements and transcription factors binding around these TSSs. This indicates that TSSs may be a better unit… read more here.
Keywords: transcription; human mouse; reference; start sites ... See more keywords
Transcription start sites experience a high influx of heritable variants fueled by early development
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DOI: 10.1038/s41467-025-66201-0
Abstract: Mutations drive evolution and genetic diversity, with the most consequential mutations occurring in coding exons and regulatory regions. However, the impact of transcription on germline mutagenesis remains poorly understood. Here, we identify a mutational hotspot… read more here.
Keywords: transcription start; start sites; germline; mutational hotspot ... See more keywords
Genome level identification of transcription start sites by nanoCAGE sequence in soybean
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DOI: 10.1038/s41597-025-06003-7
Abstract: Identification of transcription start sites (TSSs) of genes is critical for understanding promoter architecture and transcription initiation. A well-characterized and widely used method to determine TSSs is Cap Analysis of Gene Expression (CAGE). CAGE has… read more here.
Keywords: transcription start; start sites; soybean; identification transcription ... See more keywords
Computational annotation of miRNA transcription start sites
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DOI: 10.1093/bib/bbz178
Abstract: Abstract Motivation MicroRNAs (miRNAs) are small noncoding RNAs that play important roles in gene regulation and phenotype development. The identification of miRNA transcription start sites (TSSs) is critical to understand the functional roles of miRNA… read more here.
Keywords: transcription; annotation; start sites; mirna tsss ... See more keywords
Local features determine Ty3 targeting frequency at RNA polymerase III transcription start sites.
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DOI: 10.1101/gr.240861.118
Abstract: Retroelement integration into host genomes affects both genome structure and function. A goal of a considerable number of investigations is to elucidate host features that influence insertion site selection. The retrotransposon Ty3 of Saccharomyces cerevisiae… read more here.
Keywords: targeting frequency; frequency; rna polymerase; start sites ... See more keywords
Novel Transformer Networks for Improved Sequence Labeling in genomics
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DOI: 10.1109/tcbb.2020.3035021
Abstract: In genomics, a wide range of machine learning methodologies have been investigated to annotate biological sequences for positions of interest such as transcription start sites, translation initiation sites, methylation sites, splice sites and promoter start… read more here.
Keywords: start sites; sequence labeling; sequence; novel transformer ... See more keywords
Analysis of Viral Promoters for Transgene Expression and of the Effect of 5′-UTRs on Alternative Translational Start Sites in Chlamydomonas
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DOI: 10.3390/genes14040948
Abstract: Microalgae biotechnology has the potential to produce high quality bioproducts in a sustainable manner. Here, Chlamydomonas reinhardtii has shown great potential as a host for biotechnological exploitation. However, low expression of nuclear transgenes is still… read more here.
Keywords: start sites; translational start; expression; transgene expression ... See more keywords