A “Valve‐Closing” Starvation Strategy for Amplification of Tumor‐Specific Chemotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202104671
Abstract: Starvation‐dependent differential stress sensitization effect between normal and tumor cells provides a potentially promising strategy to amplify chemotherapy effects and reduce side effects. However, the conventional starvation approaches such as glucose oxidase (Gox)‐induced glucose depletion… read more here.
Keywords: closing starvation; tumor cells; starvation; strategy ... See more keywords
Cellular response during cellular starvation: A battle for cellular survivability
Sign Up to like & getrecommendations! Published in 2024 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.4101
Abstract: Cellular starvation occurs when a cell is deprived of nutrition and oxygen availability. The genesis of this state of deprivation is exclusively contingent upon the inadequacy in the supply of essential components, namely amino acids,… read more here.
Keywords: cellular starvation; starvation; cell; condition ... See more keywords
Life Stage‐ and Sex‐Specific Sensitivity to Nutritional Stress in a Holometabolous Insect
Sign Up to like & getrecommendations! Published in 2024 at "Ecology and Evolution"
DOI: 10.1002/ece3.70764
Abstract: Over the course of their lives, organisms can be repeatedly exposed to stress, which shapes their phenotype. At certain life stages, known as sensitive phases, individuals might be more receptive to such stress than at… read more here.
Keywords: life stage; stress; starvation; life ... See more keywords
Moving towards a novel therapeutic strategy for hyperammonemia that targets glutamine metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12540
Abstract: Patients with urea cycle disorders intermittently develop episodes of decompensation with hyperammonemia. Although such an episode is often associated with starvation and catabolism, its molecular basis is not fully understood. First, we attempted to elucidate… read more here.
Keywords: moving towards; novel therapeutic; therapeutic strategy; starvation ... See more keywords
Phosphorus and nitrogen starvation reveal life‐cycle specific responses in the metabolome of Emiliania huxleyi (Haptophyta)
Sign Up to like & getrecommendations! Published in 2018 at "Limnology and Oceanography"
DOI: 10.1002/lno.10624
Abstract: The coccolithophore Emiliania huxleyi is a microalga with biogeochemical and biotechnological relevance, due to its high abundance in the ocean and its ability to form intricate calcium carbonate structures. Depletion of macronutrients in oceanic waters… read more here.
Keywords: starvation; life cycle; emiliania huxleyi; cycle ... See more keywords
Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe
Sign Up to like & getrecommendations! Published in 2022 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.1303
Abstract: The fission yeast Schizosaccharomyces pombe employs two main strategies to adapt to the environment and survive when starved for nutrients. The strategies employ sporulation via sexual differentiation and extension of the chronological lifespan. When a… read more here.
Keywords: yeast schizosaccharomyces; sporulation; starvation; fission yeast ... See more keywords
Serum starvation induces sexual dimorphisms in secreted proteins of human umbilical vein endothelial cells (HUVECs) from twin pairs
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202100168
Abstract: There is growing evidence for sex and gender differences in the clinical manifestation and outcomes of human diseases. Human primary endothelial cells represent a useful cardiovascular model to study sexual dimorphisms at the cellular level.… read more here.
Keywords: endothelial cells; sexual dimorphisms; starvation; human umbilical ... See more keywords
Tumor Starvation Induced Spatiotemporal Control over Chemotherapy for Synergistic Therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Small"
DOI: 10.1002/smll.201803602
Abstract: By integrating the characteristics of each therapy modality and material chemistry, a multitherapy modality is put forward: tumor starvation triggered synergism with sensitized chemotherapy. Following starvation-induced amplification of pathological abnormalities in tumors, chemotherapy is arranged… read more here.
Keywords: chemotherapy; starvation induced; starvation; control ... See more keywords
Higher Tumor/Organ Accumulation Ratio of Porous Dual Infinite Coordination Polymer Nanocomposites for Efficient Tumor Photothermal-Starvation-Dual Hypoxia Chemo Synergistic Therapy.
Sign Up to like & getrecommendations! Published in 2024 at "Small"
DOI: 10.1002/smll.202411188
Abstract: To enhance tumor comprehensive therapeutic effect of nanomedicines, an efficient strategy that integrates polydopamine and IR780 photothermal therapy, glucose oxidase (GOx) starvation therapy, Banoxantrone (AQ4N) and Tirapazamine (TPZ) dual hypoxia chemotherapy is developed in chronological… read more here.
Keywords: dual hypoxia; therapy; higher tumor; starvation ... See more keywords
Loss of function in the Drosophila clock gene period results in altered intermediary lipid metabolism and increased susceptibility to starvation
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03441-6
Abstract: The fruit fly Drosophila is a prime model in circadian research, but still little is known about its circadian regulation of metabolism. Daily rhythmicity in levels of several metabolites has been found, but knowledge about… read more here.
Keywords: drosophila; starvation; lipid metabolism; metabolism ... See more keywords
The Mite Tyrophagus putrescentiae Hosts Population-Specific Microbiomes That Respond Weakly to Starvation
Sign Up to like & getrecommendations! Published in 2018 at "Microbial Ecology"
DOI: 10.1007/s00248-018-1224-y
Abstract: The effect of short-term nutrient deprivation was studied in five populations of the mite Tyrophagus putrescentiae with different microbiomes. The fresh weight, nutrient status, respiration, and population growth of the mites were observed for the… read more here.
Keywords: population growth; starvation; respiration; mite ... See more keywords