Estrogen inhibits starvation‐induced apoptosis in osteocytes by a redox‐independent process involving association of JNK and glutathione S‐transferase P1‐1
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12216
Abstract: Estrogen deficiency causes bone loss as a result of microdamage, oxidative stress, and osteocyte apoptosis. A relationship between oxidative stress‐induced apoptosis, c‐Jun N‐terminal kinase (JNK) activation, and expression of factors involved in bone remodeling has… read more here.
Keywords: starvation induced; apoptosis; jnk; induced apoptosis ... See more keywords
Tumor Starvation Induced Spatiotemporal Control over Chemotherapy for Synergistic Therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Small"
DOI: 10.1002/smll.201803602
Abstract: By integrating the characteristics of each therapy modality and material chemistry, a multitherapy modality is put forward: tumor starvation triggered synergism with sensitized chemotherapy. Following starvation-induced amplification of pathological abnormalities in tumors, chemotherapy is arranged… read more here.
Keywords: chemotherapy; starvation induced; starvation; control ... See more keywords
Acetylation of BmAtg8 inhibits starvation-induced autophagy initiation
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03513-y
Abstract: Silkworm (Bombyx mori) is not only a model organism for scientific studies, but also a commercial insect for agricultural production. BmAtg8 (a B. mori homolog of yeast Atg8) plays crucial roles in macroautophagy (hereafter referred… read more here.
Keywords: acetylation bmatg8; autophagy initiation; bmatg8; starvation induced ... See more keywords
Mec1 regulates PAS recruitment of Atg13 via direct binding with Atg13 during glucose starvation-induced autophagy.
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2215126120
Abstract: Mec1 is a DNA damage sensor, which performs an essential role in the DNA damage response pathway and glucose starvation-induced autophagy. However, the functions of Mec1 in autophagy remain unclear. In response to glucose starvation,… read more here.
Keywords: glucose starvation; atg13; induced autophagy; starvation induced ... See more keywords
Starvation-induced sleep suppression requires the Drosophila brain nutrient sensor.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurogenetics"
DOI: 10.1080/01677063.2023.2203489
Abstract: Animals increase their locomotion activity and reduce sleep duration under starved conditions. This suggests that sleep and metabolic status are closely interconnected. The nutrient and hunger sensors in the Drosophila brain, including diuretic hormone 44… read more here.
Keywords: sleep suppression; brain; starvation induced; induced sleep ... See more keywords
Iron uptake proteins in algae and the role of Iron Starvation-Induced Proteins (ISIPs)
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Phycology"
DOI: 10.1080/09670262.2020.1744039
Abstract: ABSTRACT Iron is one of the most abundant elements on Earth, and it is essential for life. Despite the abundance of iron, its chemistry leads to very limited bioavailability, which has resulted in the evolution… read more here.
Keywords: starvation induced; iron uptake; induced proteins; uptake proteins ... See more keywords
The autophagy-resistant Mycobacterium tuberculosis Beijing strain upregulates KatG to evade starvation-induced autophagic restriction
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens and Disease"
DOI: 10.1093/femspd/ftac004
Abstract: Abstract Mycobacterium tuberculosis utilizes several mechanisms to block phagosome–lysosome fusion to evade host cell restriction. However, induction of host cell autophagy by starvation was shown to overcome this block, resulting in enhanced lysosomal delivery to… read more here.
Keywords: induced autophagic; restriction; starvation; tuberculosis beijing ... See more keywords
Insulin/IGF-dependent Wnt signaling promotes formation of germline tumors and other developmental abnormalities following early-life starvation in Caenorhabditis elegans.
Sign Up to like & getrecommendations! Published in 2022 at "Genetics"
DOI: 10.1093/genetics/iyac173
Abstract: The Developmental Origins of Health and Disease (DOHaD) hypothesis postulates that early-life stressors can predispose people to disease later in life. In the roundworm Caenorhabditis elegans, prolonged early-life starvation causes germline tumors, uterine masses and… read more here.
Keywords: life starvation; early life; starvation; wnt signaling ... See more keywords
Differential requirements for Gcn5 and NuA4 HAT activities in the starvation-induced versus basal transcriptomes.
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic acids research"
DOI: 10.1093/nar/gkad099
Abstract: The histone acetyltransferase (HAT) subunit of coactivator complex SAGA, Gcn5, stimulates eviction of promoter nucleosomes at certain highly expressed yeast genes, including those activated by transcription factor Gcn4 in amino acid-deprived cells; however, the importance… read more here.
Keywords: basal transcriptomes; transcription; hat activities; starvation induced ... See more keywords
Starvation‐induced autophagy in Spodoptera frugiperda Sf9 ovarian cells
Sign Up to like & getrecommendations! Published in 2019 at "Physiological Entomology"
DOI: 10.1111/phen.12279
Abstract: Autophagy controls insect development and can be targeted for pest control in agriculture. In the present study, starvation‐induced autophagy is investigated in the insect species Spodoptera frugiperda. Bioinformatics analysis and a search of the EST… read more here.
Keywords: sf9; starvation induced; starvation; spodoptera frugiperda ... See more keywords
Starvation-induced changes in somatic insulin/IGF-1R signaling drive metabolic programming across generations
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.ade1817
Abstract: Exposure to adverse nutritional and metabolic environments during critical periods of development can exert long-lasting effects on health outcomes of an individual and its descendants. Although such metabolic programming has been observed in multiple species… read more here.
Keywords: metabolic programming; igf; starvation induced; across generations ... See more keywords