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   Articles with "stat" as a keyword



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Interferon functional analog activates antiviral Jak/Stat signaling through integrin in an arthropod.

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recommendations! Published in 2021 at "Cell reports"

DOI: 10.1016/j.celrep.2021.109761

Abstract: Drosophila Vago is a small antiviral peptide. Its ortholog in Culex mosquito was found to be an interferon-like cytokine that limits virus replication through activating Jak/Stat signaling. However, this activation is independent of Domeless, the… read more here.

Keywords: stat signaling; integrin; jak stat; mjvago ... See more keywords
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27-Hydroxycholesterol induces invasion and migration of breast cancer cells by increasing MMP9 and generating EMT through activation of STAT-3.

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recommendations! Published in 2017 at "Environmental toxicology and pharmacology"

DOI: 10.1016/j.etap.2017.02.001

Abstract: Breast carcinoma plays a vital role in the reasons of global women's death. ER-related invasion and migration play an important part in the development and prognosis of breast cancer. Here, we found that 27-Hydroxycholesterol (27HC)… read more here.

Keywords: mmp9; breast; invasion; invasion migration ... See more keywords
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Avoiding Cribari gridlock 2: The standardized triage assessment tool outperforms the Cribari matrix method in 38 adult and pediatric trauma centers.

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recommendations! Published in 2020 at "Injury"

DOI: 10.1016/j.injury.2020.09.027

Abstract: OBJECTIVES The Cribari Matrix Method (CMM) is the current standard to identify over/undertriage but requires manual trauma triage reviews to address its inadequacies. The Standardized Triage Assessment Tool (STAT) partially emulates triage review by combining… read more here.

Keywords: standardized triage; trauma; cribari matrix; stat ... See more keywords
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Potentiostatic way to fabricate Li2Sx cathode with suppressed polysulfide formation

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recommendations! Published in 2018 at "Journal of Power Sources"

DOI: 10.1016/j.jpowsour.2018.07.107

Abstract: Abstract The usage of Li metal in lithium sulfur (Li-S) battery has largely hampered the application of Li-S battery due to the formation of Li dendrite during cycling. Here, a novel potentiostatic (p-stat) lithiation method… read more here.

Keywords: li2sx cathode; fabricate li2sx; cathode; formation ... See more keywords
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Targeting STATs in neuroinflammation: The road less traveled!

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recommendations! Published in 2019 at "Pharmacological Research"

DOI: 10.1016/j.phrs.2018.12.004

Abstract: &NA; JAK/STAT transduction pathway is a highly conserved pathway implicated in regulating cellular proliferation, differentiation, survival and apoptosis. Dysregulation of this pathway is involved in the onset of autoimmune, haematological, oncological, metabolic and neurological diseases.… read more here.

Keywords: stats neuroinflammation; neuroinflammation road; less traveled; targeting stats ... See more keywords
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Antagonizing cytokine-mediated JAK-STAT signaling by porcine reproductive and respiratory syndrome virus

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recommendations! Published in 2017 at "Veterinary Microbiology"

DOI: 10.1016/j.vetmic.2016.12.036

Abstract: Abstract Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway is activated by myriad cytokines, which are involved in regulation of cell growth, proliferation, differentiation, apoptosis, angiogenesis, immunity and inflammatory response. Because of… read more here.

Keywords: response; stat signaling; jak stat; stat ... See more keywords
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Potential Impact of C-STAT for Prehospital Stroke Triage up to 24 Hours on a Regional Stroke System

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recommendations! Published in 2019 at "Prehospital Emergency Care"

DOI: 10.1080/10903127.2019.1676343

Abstract: Abstract Background and Purpose: Thrombectomy for large vessel occlusion acute ischemic stroke (AIS-LVO) may benefit patients up to 24 hour since last known normal (LKN). Prehospital tools, like the Cincinnati Stroke Triage Assessment Tool (C-STAT), are… read more here.

Keywords: impact; stat; ais lvo; triage ... See more keywords
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Streamlining Activated Clotting Time Measuring Systems: Comparison of Three Point-of-Care Systems to the i-STAT.

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recommendations! Published in 2017 at "American Journal of Clinical Pathology"

DOI: 10.1093/ajcp/aqw191.047

Abstract: Point-of-care (POC) activated clotting time (ACT) testing allows for the rapid and reliable assessment of hemostasis in patients undergoing heparin therapy. This is crucial for the safe management of patients during cardiopulmonary bypass, ablation in… read more here.

Keywords: act; hemochron; gem pcl; stat ... See more keywords
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Anti‐growth and pro‐apoptotic effects of dasatinib on human oral cancer cells through multi‐targeted mechanisms

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recommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.16782

Abstract: Dasatinib is an inhibitor of Src that has anti‐tumour effects on many haematological and solid cancers. However, the anti‐tumour effects of dasatinib on human oral cancers remain unclear. In this study, we investigated the effects… read more here.

Keywords: oral cancer; effects dasatinib; stat; cancer cells ... See more keywords
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JAK/STAT: Why choose a classical or an alternative pathway when you can have both?

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recommendations! Published in 2022 at "Journal of cellular and molecular medicine"

DOI: 10.1111/jcmm.17168

Abstract: A subset of cytokines triggers the JAK-STAT pathway to exert various functions such as the induction of inflammation and immune responses. The receptors for these cytokines are dimers/trimers of transmembrane proteins devoid of intracellular kinase… read more here.

Keywords: jak stat; stat; cytokine receptors; pathway ... See more keywords
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JAK‐STAT core cancer pathway: An integrative cancer interactome analysis

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recommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.17228

Abstract: Through a comprehensive review and in silico analysis of reported data on STAT‐linked diseases, we analysed the communication pathways and interactome of the seven STATs in major cancer categories and proposed rational targeting approaches for… read more here.

Keywords: stat core; stat; analysis; jak stat ... See more keywords