Articles with "stat" as a keyword



Interferon functional analog activates antiviral Jak/Stat signaling through integrin in an arthropod.

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Published in 2021 at "Cell reports"

DOI: 10.1016/j.celrep.2021.109761

Abstract: Drosophila Vago is a small antiviral peptide. Its ortholog in Culex mosquito was found to be an interferon-like cytokine that limits virus replication through activating Jak/Stat signaling. However, this activation is independent of Domeless, the… read more here.

Keywords: stat signaling; integrin; jak stat; mjvago ... See more keywords

27-Hydroxycholesterol induces invasion and migration of breast cancer cells by increasing MMP9 and generating EMT through activation of STAT-3.

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Published in 2017 at "Environmental toxicology and pharmacology"

DOI: 10.1016/j.etap.2017.02.001

Abstract: Breast carcinoma plays a vital role in the reasons of global women's death. ER-related invasion and migration play an important part in the development and prognosis of breast cancer. Here, we found that 27-Hydroxycholesterol (27HC)… read more here.

Keywords: mmp9; breast; invasion; invasion migration ... See more keywords

Avoiding Cribari gridlock 2: The standardized triage assessment tool outperforms the Cribari matrix method in 38 adult and pediatric trauma centers.

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Published in 2020 at "Injury"

DOI: 10.1016/j.injury.2020.09.027

Abstract: OBJECTIVES The Cribari Matrix Method (CMM) is the current standard to identify over/undertriage but requires manual trauma triage reviews to address its inadequacies. The Standardized Triage Assessment Tool (STAT) partially emulates triage review by combining… read more here.

Keywords: standardized triage; trauma; cribari matrix; stat ... See more keywords

Potentiostatic way to fabricate Li2Sx cathode with suppressed polysulfide formation

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Published in 2018 at "Journal of Power Sources"

DOI: 10.1016/j.jpowsour.2018.07.107

Abstract: Abstract The usage of Li metal in lithium sulfur (Li-S) battery has largely hampered the application of Li-S battery due to the formation of Li dendrite during cycling. Here, a novel potentiostatic (p-stat) lithiation method… read more here.

Keywords: li2sx cathode; fabricate li2sx; cathode; formation ... See more keywords
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Targeting STATs in neuroinflammation: The road less traveled!

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Published in 2019 at "Pharmacological Research"

DOI: 10.1016/j.phrs.2018.12.004

Abstract: &NA; JAK/STAT transduction pathway is a highly conserved pathway implicated in regulating cellular proliferation, differentiation, survival and apoptosis. Dysregulation of this pathway is involved in the onset of autoimmune, haematological, oncological, metabolic and neurological diseases.… read more here.

Keywords: stats neuroinflammation; neuroinflammation road; less traveled; targeting stats ... See more keywords

Antagonizing cytokine-mediated JAK-STAT signaling by porcine reproductive and respiratory syndrome virus

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Published in 2017 at "Veterinary Microbiology"

DOI: 10.1016/j.vetmic.2016.12.036

Abstract: Abstract Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway is activated by myriad cytokines, which are involved in regulation of cell growth, proliferation, differentiation, apoptosis, angiogenesis, immunity and inflammatory response. Because of… read more here.

Keywords: response; stat signaling; jak stat; stat ... See more keywords

Extracting the femtometer structure of strange baryons using the vacuum polarization effect

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Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-51802-y

Abstract: One of the fundamental goals of particle physics is to gain a microscopic understanding of the strong interaction. Electromagnetic form factors quantify the structure of hadrons in terms of charge and magnetization distributions. While the… read more here.

Keywords: stat; effect; structure; document ... See more keywords

JAK-STAT signaling maintains homeostasis in T cells and macrophages

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Published in 2024 at "Nature Immunology"

DOI: 10.1038/s41590-024-01804-1

Abstract: Immune cells need to sustain a state of constant alertness over a lifetime. Yet, little is known about the regulatory processes that control the fluent and fragile balance that is called homeostasis. Here we demonstrate… read more here.

Keywords: stat; homeostasis; stat signaling; cells macrophages ... See more keywords

Canagliflozin alleviates acetaminophen-induced renal and hepatic injury in mice by modulating the p-GSK3β/Fyn-kinase/Nrf-2 and p-AMPK-α/STAT-3/SOCS-3 pathways

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Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-024-82163-7

Abstract: Despite the fact that canagliflozin (Cana), a sodium-glucose cotransporter 2 inhibitor, is an anti-diabetic medication with additional effects on the kidney, there is limited experimental data to deliberate its hepato-reno-protective potentiality. Acetaminophen (APAP) overdose remains… read more here.

Keywords: stat; socs; apap; gsk3 fyn ... See more keywords

Potential Impact of C-STAT for Prehospital Stroke Triage up to 24 Hours on a Regional Stroke System

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Published in 2019 at "Prehospital Emergency Care"

DOI: 10.1080/10903127.2019.1676343

Abstract: Abstract Background and Purpose: Thrombectomy for large vessel occlusion acute ischemic stroke (AIS-LVO) may benefit patients up to 24 hour since last known normal (LKN). Prehospital tools, like the Cincinnati Stroke Triage Assessment Tool (C-STAT), are… read more here.

Keywords: impact; stat; ais lvo; triage ... See more keywords

Streamlining Activated Clotting Time Measuring Systems: Comparison of Three Point-of-Care Systems to the i-STAT.

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Published in 2017 at "American Journal of Clinical Pathology"

DOI: 10.1093/ajcp/aqw191.047

Abstract: Point-of-care (POC) activated clotting time (ACT) testing allows for the rapid and reliable assessment of hemostasis in patients undergoing heparin therapy. This is crucial for the safe management of patients during cardiopulmonary bypass, ablation in… read more here.

Keywords: act; hemochron; gem pcl; stat ... See more keywords