MDA5 against enteric viruses through induction of interferon-like response partially via the JAK-STAT cascade.
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DOI: 10.1016/j.antiviral.2020.104743
Abstract: Enteric viruses including hepatitis E virus (HEV), human norovirus (HuNV), and rotavirus are causing global health issues. The host interferon (IFN) response constitutes the first-line defense against viral infections. Melanoma Differentiation-Associated protein 5 (MDA5) is… read more here.
Keywords: stat cascade; enteric viruses; jak stat; response ... See more keywords