1026 - JAK/STAT SIGNALLING, STEM CELL SUBVERSION AND MYELOID MALIGNANCIES
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Hematology"
DOI: 10.1016/j.exphem.2019.06.264
Abstract: Our research focuses on the mechanisms whereby blood stem cells are subverted during the genesis of haematological malignancies. We have increasingly concentrated on JAK/STAT signalling which is dysregulated in many cancers and plays a key… read more here.
Keywords: jak stat; stem cell; stem; stat signalling ... See more keywords
The role of JAK-STAT signalling activation in hypertrophied ligamentum flavum.
Sign Up to like & getrecommendations! Published in 2020 at "World neurosurgery"
DOI: 10.1016/j.wneu.2020.02.024
Abstract: OBJECTIVE Although previous studies have reported the expression of JAK1, STAT3 and phosphorylated p-STAT3 in hypertrophied ligamentum flavum (LF), the role of the JAK/STAT signalling pathway in hypertrophied LF has not been fully elucidated. The… read more here.
Keywords: jak; ligamentum flavum; jak stat; stat signalling ... See more keywords
212 Suppressor of cytokine signalling 3 (socs3) interaction with cavin-1 links socs3 function and cavin-1 stability
Sign Up to like & getrecommendations! Published in 2017 at "Heart"
DOI: 10.1136/heartjnl-2017-311726.210
Abstract: Caveolae are lipid raft microdomains essential for the compartmentalisation and regulation of several signalling pathways e.g. JAK/STAT signalling. Disruption of caveolae is a significant factor in multiple disorders including muscular dystrophy, cardiovascular disease, and cancer.… read more here.
Keywords: caveolae; socs3; jak stat; cavin ... See more keywords
JAK-STAT Signalling Pathway in Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12071971
Abstract: JAK-STAT signalling is a cornerstone to cancer progression, either as a tumour intrinsic driver of cancer growth/metastasis, or as a modulator of immune surveillance. This Special Issue highlights new research findings underlying the contribution of… read more here.
Keywords: jak; issue; jak stat; stat signalling ... See more keywords