The involvement of protein TNFSF18 in promoting p‐STAT1 phosphorylation to induce coronary microcirculation disturbance in atherosclerotic mouse model
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DOI: 10.1002/ddr.21735
Abstract: The inflammation of coronary endothelium was critically involved in the pathogenesis of atherosclerosis. The purpose of the study was to reveal the roles of TNFSF18 in promoting p‐STAT1 phosphorylation to induce disturbance of coronary microcirculation… read more here.
Keywords: tnfsf18; model; mouse model; stat1 phosphorylation ... See more keywords
Drug screening identified gemcitabine inhibiting hepatitis E virus by inducing interferon-like response via activation of STAT1 phosphorylation.
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DOI: 10.1016/j.antiviral.2020.104967
Abstract: Exposure to hepatitis E virus (HEV) bears a high risk of developing chronic infection in immunocompromised patients, including organ transplant recipients and cancer patients. We aim to identify effective anti-HEV therapies through screening and repurposing… read more here.
Keywords: response; gemcitabine; hepatitis; activation ... See more keywords