Methanethiosulfonate derivatives as ligands of the STAT3-SH2 domain
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DOI: 10.1080/14756366.2016.1252757
Abstract: Abstract With the aim to discover new STAT3 direct inhibitors, potentially useful as anticancer agents, a set of methanethiosulfonate drug hybrids were synthesized. The in vitro tests showed that all the thiosulfonic compounds were able… read more here.
Keywords: derivatives ligands; sh2 domain; methanethiosulfonate derivatives; stat3 sh2 ... See more keywords