Study of Allosteric Transitions of Human P-Glycoprotein by Using the Two-State Anisotropic Network Model
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DOI: 10.3389/fmed.2022.815355
Abstract: Human P-glycoprotein (P-gp) is a kind of ATP-binding cassette (ABC) transporters. Once human P-gp is overexpressed in tumor cells, which can lead to tumor multidrug resistance (MDR). However, the present experimental methods are difficult to… read more here.
Keywords: state; network model; human glycoprotein; two state ... See more keywords