Irbesartan desmotropes: Solid-state characterization, thermodynamic study and dissolution properties
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical Analysis"
DOI: 10.1016/j.jpha.2019.07.001
Abstract: Irbesartan (IBS) is a tetrazole derivative and antihypertensive drug that has two interconvertible structures, 1H- and 2H-tautomers. The difference between them lies in the protonation of the tetrazole ring. In the solid-state, both tautomers can… read more here.
Keywords: solid state; state; microscopy; characterization thermodynamic ... See more keywords
Solid-State Characterization and Compatibility Studies of Penciclovir, Lysine Hydrochloride, and Pharmaceutical Excipients
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DOI: 10.3390/ma12193154
Abstract: The physical and chemical characterization of the solid-state properties of drugs and excipients is fundamental for planning new formulations and developing new strategies for the treatment of diseases. Techniques such as differential scanning calorimetry, thermogravimetry,… read more here.
Keywords: solid state; state characterization; compatibility; penciclovir lysine ... See more keywords
Solid-state characterization of ibuprofen-isonicotinamide cocrystals prepared by electrospraying and solvent evaporation.
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic delivery"
DOI: 10.4155/tde-2022-0072
Abstract: Aim: Electrospraying (ELS) was used to prepare micronized ibuprofen-isonicotinamide cocrystal (IBU-INA-ELS) and its properties were compared with the solvent evaporated cocrystal (IBU-INA-SE). Methods: Solid-state characterization of crystalline phase, production yield, particle size, powder flow, wettability,… read more here.
Keywords: dissolution; ibu ina; solid state; state characterization ... See more keywords
Solid State Characterization and Tableting Studies of Ethanol Based Cocrystals of Fenofibrate with Nicotinamide
Sign Up to like & getrecommendations! Published in 2018 at "Indian Journal of Pharmaceutical Education and Research"
DOI: 10.5530/ijper.52.1.8
Abstract: Objectives: The pharmaceutical cocrystals can be defined as dissociable “API-excipient” molecular complexes or Co-crystals are solids that are crystalline materials composed of two or more molecules in the same crystal lattice as per U.S. Department… read more here.
Keywords: solid state; state characterization; spectroscopy; fenofibrate nicotinamide ... See more keywords