The role of surface energy heterogeneity on crystal morphology during solid-state crystallization at the amorphous atazanavir–water interface
Sign Up to like & getrecommendations! Published in 2020 at "CrystEngComm"
DOI: 10.1039/c9ce02007a
Abstract: Enhancing dissolution of pharmaceutical products via amorphous formulations is a common strategy for improving bioavailability for drugs with low aqueous solubility. Crystallization of the amorphous material during storage as well as from solution during dosing… read more here.
Keywords: solid state; crystallization amorphous; crystallization; state crystallization ... See more keywords
Multistep nucleation visualized during solid-state crystallization.
Sign Up to like & getrecommendations! Published in 2022 at "Materials horizons"
DOI: 10.1039/d2mh00174h
Abstract: Mechanisms of nucleation have been debated for more than a century, despite successes of classical nucleation theory. The nucleation process has been recently argued as involving a nonclassical mechanism (the "two-step" mechanism) in which an… read more here.
Keywords: solid state; state crystallization; multistep nucleation; nucleation ... See more keywords