A high content screening assay for identifying inhibitors against active and dormant state intracellular Mycobacterium tuberculosis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2019.105687
Abstract: The antitubercular drug development pipeline could start with an in vitro investigation of several compounds to examine their effect on active and dormant state Mycobacterium tuberculosis (Mtb). However, in vitro screening of dormant state bacilli… read more here.
Keywords: state; dormant state; active dormant; state intracellular ... See more keywords
A new approach for ratiometric in vivo calcium imaging of microglia
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-05952-3
Abstract: Microglia, resident immune cells of the brain, react to the presence of pathogens/danger signals with a large repertoire of functional responses including morphological changes, proliferation, chemotaxis, production/release of cytokines, and phagocytosis. In vitro studies suggest… read more here.
Keywords: vivo; state intracellular; steady state; ca2 ... See more keywords